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From Semaglutide and Tirzepatide reduce alcohol consumption in individuals with obesity: In the remote study, we observe a significantly lower self-reported intake of alcohol, drinks per drinking episode, binge drinking odds, Alcohol Use Disorders Identification Test (AUDIT) scores, and stimulating, and sedative effects in the Semaglutide or Tirzepatide group when compared to prior to starting medication timepoint (within-subjects) and the control group (between-subjects)
But, studies have found that tirzepatide shows a more significant reduction in body weight and fat mass
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The findings align with recent studies that showed similar results when comparing SGLT2 inhibitors and GLP-1RAs in patients with type 2 diabetes, where the NAFLD status was unknown [30]
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